Getting children through fertility treatments threatens men with prostate cancer

UNITED STATES, WASHINGTON (OBSERVATORY) — Men who have fertility problems and are struggling with treatments to get children are at a higher risk of developing prostate cancer, a new study suggests.

The researchers analyzed data from more than a million men who had children between 1994 and 2014 in Sweden, and found that those who had children through IVF and other fertility treatments were 64 percent more likely to develop the disease.

Although the exact relationship between prostate cancer, low fertility and infertility is unclear, scientists believe both can be affected by major sex hormones, and genetic abnormalities in the Y chromosome may be the cause.

Deletion of DNA on this chromosome is known to cause male infertility, while genes on the same chromosome have been linked to prostate cancer.

The study, published in the British medical journal BMJ, was conducted by Lund University in Sweden and Sofia Medical University in Bulgaria, in which researchers analyzed nearly 1.2 million births over two decades, and found that men using fertility therapy called ICSI. They were 64% more likely to develop prostate cancer, and their risk before age 55 was 86% higher.

The results also found that the incidence of this disease is 33% higher in the case of undergoing IVF, a process that results in IVF, and 51% more likely to develop this type of cancer at a young age.

Experts claim that the findings suggest that infertile men undergoing fertility treatments should benefit from early screening and long-term monitoring of prostate cancer.

“Men who have achieved paternity dreams through supported reproductive techniques, especially ICSI, are at high risk of developing early prostate cancer,” said lead researcher Yahya al-Jabari of Lund University.

Alan Passy, ​​a fertility expert and a professor of masculinity at the University of Sheffield, said the study adds evidence to the theory of a “canary sparrow in a coal mine” (meaning something early warning of danger) by showing that Swedish men who became parents by reproductive techniques Assistance, such as ICSI, is at increased risk for prostate cancer later in life.

Based on these findings, he added that all men diagnosed with fertility in their 20s and 30s should be given a detailed explanation of what could happen in them in their fifties and sixties, so that they could recognize potential future health problems early on and be encouraged to see a doctor.


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