New way to treat a terminal illness just discovered

UNITED STATES (OBSERVATORY NEWS) — University of Monash and Cambridge scientists have discovered a way to treat Huntington’s untreatable and fatal syndrome, which affects the central nervous system.

According to EurekAlert, researchers have determined the part of the RNA that is responsible for regulating the accumulation of protein assemblies that occur in people with the disease in neurons, which prevents them from performing their functions normally.

For example, the miR-1 molecule is present in non-significant quantities in people with Parkinson’s disease. These RNA parts are the same in humans and Caenorhabditis elegans, although evolution separated them 600 million years ago.

Researchers found that eradication of miR-1 from worms led to the production of actively damaged proteins.

The researchers also discovered that the miR-1 molecule controls the structure of TBC-7, which in turn manages the autophagy process (the process of removing damaged cells and their components). The same thing happens in human cells.

The production of a large amount of miR-1 molecules can be influenced by the interferon- β protein, which is normally produced by cells of the human body when infected with a viral infection.


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