UNITED STATES, WASHINGTON (OBSERVATORY HEALTH) — Researchers from the American University of Vanderbilt have proposed a way to combat the growth of malignant tumors.
Scientists have focused on the properties of the proteins encoded by the MYC gene. It serves as an oncogene for many tumors, for example, mutations inside this gene cause Burkitt’s lymphoma.
Previously, experts tried to directly block the activity of these proteins, but to no avail.
Professor William Tancy and his colleagues at Vanderbilt University went further and studied the interaction of MYC with the cofactor WDR5 in a laboratory model of Burkitt’s lymphoma, which is particularly aggressive in patients. Breaking this connection, scientists noticed that the cancer began to rapidly regress.
Researchers have suggested that this discovery may contribute to the emergence of new methods of drug therapy. In a press release of the scientific work, it is noted that in the USA alone, the share of MYC oncogenic mutations accounts for about one hundred thousand deaths per year.
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